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Lack of energy is a common symptom with many possible causes, including anemia, sleep disorders, an underactive thyroid gland, and depression. Fatigue may also accompany other illnesses, including diabetes, congestive heart failure, and mononucleosis. In some cases, fatigue is a symptom of chronic fatigue syndrome, a condition that begins with a flu-like system but persists for six months or longer. A physical examination, medical history, and blood tests may be recommended to determine the underlying cause of persistent fatigue.
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