- Elong ateel occiput
- Over lapping digits
- Rocker Haltom feet
- Congenital heart defects
- Ventricular septal defect
- Lutellectual disability
- Apnea
- Omphalo cell
- Mental retarclation
- Growth deficiency
- Microcepthelly
- Microqanthia
- Left lip/Polate
- Palpebral fissures
- Ocular lypentelorism
- Extra chromosome is present because of non-dysfunction
- Polymorphisms in mothers
- Mlthylene tetrahydrofolate reductive gets
- Advancing maternal age
- Small positive association of paternal age
- Trisomy 18 cannot be prevented before conception.
- Close care of in faint.
- Naso gastric and gastronomy supplementation for feeding.
- Corrective and palliative heart surgery.


