Chancroid

  • Also known as soft chancre.
  • Acute, autoinoculable, STI caused by Hemophilus ducreyi.
  • Males affected more commonly.
  • Incubation period: 3-7 days
  • Sites: Frenulum, prepuce, coronal sulcus in male and vulva, vestibule in females.
  • Painful genital ulcers
  • Non-indurated,
  • Bleed on touch
  • Yellow ragged edges
  • Edema of prepuce
  • Tender sometimes suppurative inguinal lymphadenopathy (unilateral in majority).

Secondary infection, ulceration

Hemophilus ducreyi (Pleomorphic gram negative facultative, anaerobic bacillus.)

  • Maintain sexual hygiene
  • Use of protection
  • 10% of patients are co-infected with either HSV or T. pallidum.
  • Males >> females.
  • Occurs in sustained, urban outbreaks.
  • Associated with female commercial sex workers and “sex-for-drugs” trade.

How is it diagnosed?

  • Microscopy
  • Gram stain , Fluorescent labelled monoclonal antibody detection
  • “School of fish” or “rail road track” appearance (gram stain).
  • Serology : ELISA, Immuno dot technique
  • Molecular techniques - PCR
  • Histopathology
  • Growth is best in Mueller Hinton agar supplemented with chocolate horse blood.

How is it treated?

  • Azithromycin 1 gm orally single dose
  • Ceftriaxone 250 mg IM in a single dose
  • Ciprofloxacin 500 mg twice daily x 3 days

Consult with experienced Doctors

JNU is home to some of the most eminent doctors in the world, most of whom are pioneers in their respective arenas and are renowned for developing innovative and revolutionary procedures
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