Urticaria

Angioedema, Swelling in laryngeal mucosa

Exogenous (Allergens and Pseudoallergens)

• Inhalants: pollens, house dust, fungi, dander.
• Ingestants: fish, egg, brinjal , soy, milk, chocolate, nuts, (pseudoallergens - food additives, dyes, preservatives, flavors).
• Drugs : NSAIDs, Polymyxin, Vancomycin, Morphine, codeine, Penicillins, Cephalosporins
• Food likely to cause urticarial: Nuts, fish, chocolates, spices [Act through type I hypersensitivity (IgE mediated)]
• Food additives such as sodium benzoate, salicylates
• Act by pseudoallergic mechanism, direct mast cell activators

Endogenous

• Infections: Gastrointestinal, respiratory, urinary tract infections, Bacterial, protozoal, helminthic, viral (CMV, EBV, HSV)
• Systemic diseases: Hashimoto’s thyroiditis, Systemic lupus erythematosus, Chronic active hepatitis, Malignancies

Avoid triggering factors

Thyroid disease, Atopic disorders, Vitiligo, Pernicious anemia, Rheumatoid arthritis