Exchange Transfusion

It decreases the risk of bilirubin encephalopathy by:

  • Reducing total bilirubin load.
  • Increasing the binding sites of plasma albumin.
  • Shifting bilirubin out of plasma.
  • Removes sensitized RBC.

Umbilical venous catheterization is done 5‐10 ml aliquots are removed and replaced sequentially until about twice the blood volume of neonate has been replaced (double volume exchange transfusion)

Choice of blood:

  • ABO Incompatibility: use O +ve blood. Ideal is O +ve cells suspended in AB plasma
  • Rh ISO-immunization: In emergency use O ‐ve blood. Ideal is O ‐ve blood suspended in AB plasma
  • Thromocytopenia
  • Hypocalcemia
  • Hypoglycemia
  • Hyperkalemia
  • Hyponatremia
  • Sepsis
  • Necrotising enterocolitis

Consult with experienced Doctors

JNU is home to some of the most eminent doctors in the world, most of whom are pioneers in their respective arenas and are renowned for developing innovative and revolutionary procedures